Peptide Playbook

Peptides explained.
Protocols that work.

Research-backed guides and practical protocols for peptides — translated from the science, without the hype.

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Longevity 15 min

Epitalon: The Telomere Peptide With One Lab, One Researcher, and a Claim That Would Change Medicine — If It's True

Epitalon claims to activate telomerase and extend lifespan. Nearly all research comes from one Russian scientist who held 196 patents. A 2025 independent study just confirmed the mechanism — and found a cancer concern.

Fundamentals 15 min

PT-141: The Peptide That Targets Desire, Not Blood Flow — and Why Its FDA Approval Barely Made a Dent

PT-141 is the only FDA-approved peptide for sexual desire. It works through the brain, not blood flow. But a 40% nausea rate and $290/dose explain why almost nobody uses it.

Muscle Growth 15 min

CJC-1295 + Ipamorelin: The Peptide Clinic Staple That's Never Been Tested as a Combination

Every anti-aging clinic sells this stack. Zero studies test it together. GH goes up — but does that actually translate to the results you want? Here's the honest breakdown.

Skin & Hair 15 min

GHK-Cu: The Copper Peptide Your Body Makes Less of Every Year — and Why That Might Matter More Than You Think

GHK-Cu modulates 4,000+ genes, outperforms retinol in clinical trials, and declines 60% as you age. From skincare to longevity, here's what the evidence shows.

Muscle Growth 15 min

MK-677: The Oral GH Booster With 11 Human Trials, a Failed Alzheimer's Study, and an Appetite Problem

MK-677 has more clinical data than most peptides combined — 11 human trials, a 2-year RCT, and 563 Alzheimer's patients. Here's what all that data actually shows.

Muscle Growth 16 min

The Wolverine Stack: BPC-157 + TB-500 — What the Evidence Actually Shows

The Wolverine Stack is the most popular peptide combination in biohacking. BPC-157 has 3 human studies. TB-500 has more. Here's what you need to know before trying it.